Angiogenesis Foundation
News & MediaAntiangiogenic Substances in Blackberries, Licorice May Aid Cancer Prevention
Two recent studies suggest that naturally occurring antiangiogenic molecules present in black raspberries and licorice may have a role in preventing some types of cancer. In the first study published in the journal Cancer Prevention(1), researchers at the Ohio State...
FDA Drug Panel Unanimously Recommends Bevacizumab (Avastin) for Approval to Treat Brain Cancer
The FDA's Oncologic Drugs Advisory Committee (ODAC) unanimously recommended accelerated approval for bevacizumab (Avastin) for the treatment of glioblastoma multiforme (GBM), an aggressive and nearly uniformly fatal form of brain cancer. The drug's manufacturer,...
Adult Stem Cells Show Efficacy in Treating Heart Disease
Preliminary data from the largest CD34+ adult stem cell study for heart disease has shown the first evidence that delivering a potent form of autologous (patient-derived) adult stem cells into the heart muscle of patients with severe angina (chest pain due to blocked...
Angiogenesis Marker Predicts Disease Progression in Melanoma
German researchers have found that high circulating levels of angiopoietin-2 (Ang-2), a naturally occurring angiogenesis stimulator, correlates with tumor progression and reduced survival in patients with advanced (stage III and IV) melanoma. The findings were...
Streamlining blood vessel walls could lead to new cancer-fighting strategy
New research indicates that tumor blood vessels contain a protein sensor that detects minute changes in oxygen levels in tissues. These tumor vessels respond to the changes by becoming either more or less porous, which significantly influences the ability of cancer...
Lowering Serum Cholesterol Suppresses Angiogenesis and Tumor Growth
Lowering serum cholesterol appears to suppress tumor angiogenesis and the growth of prostate tumors in mice, according to a new study appearing in the March 2009 issue of The American Journal of Pathology. High cholesterol not only leads to atherosclerosis and heart...
Tumors found to use growth factor receptor-containing microvesicles to stimulate angiogenesis
A team of cancer researchers at the Research Institute of the McGill University Health Centre (MUHC) at the Montreal Children's Hospital has discovered a new mechanism by which cancerous tumors stimulate the growth of the blood vessels that feed them, a process called...
Angiogenic Adult Stem Cells from Bone Marrow Shown to Heal Nerves
Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found. The results are described in the February 10th issue of the journal Circulation. The majority of people with...
Drugs the Block Angiogenesis May Improve Outcomes of Patients with Rare Type of Ovarian Cancer
Researchers from The University of Texas M.D. Anderson Cancer Center have found that increased angiogenesis and vascular endothelial growth factor (VEGF) expression are associated with poor survival in women with sex cord-stromal ovarian tumors. The data was presented...
Common beta-blocker medications might slow tumor growth in some cancer types
New research published in the journal Brain, Behavior, and Immunity suggests that the use of commonly prescribed blood pressure medicines called beta-blockers might slow the development of malignant melanoma, a particularly aggressive form of skin cancer. Researchers...
How chemotherapy drugs block blood vessel growth, slow cancer spread
Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth. Their findings, reported online this week at the Proceedings of the National Academy of...
Control of blood vessels a possible weapon against obesity
Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study published in the journal Cell Metabolism. Scientists now hope to learn how to control blood vessel development in humans...
Inflammatory Factors Found in High Levels in Eyes of People with Diabetic Retinopathy
In a new study published in the January 2009 issue of the journal Ophthalmology, Japanese researchers found high levels of inflammatory factors, including vascular endothelial growth factor (VEGF), the primary proangiogenic growth factor, in the vitreous of people...
The Angiogenesis Foundation Mourns the Death of Sir Roger Moore, KBE
It is with great sadness and a profound sense of loss that the Angiogenesis Foundation mourns the passing of Sir Roger Moore, KBE, at the age of 89. Sir Roger served as a Special Advisor and good friend to the Angiogenesis Foundation, starring in a video about disease...