Our Global Initiatives
Angiogenesis is the common denominator impacting more than 70 diseases.
Angiogenesis is a critical factor impacting more than 70 diseases, including cancer, heart disease, obesity, blindness, diabetes, chronic wounds, Alzheimer’s and many more. When angiogenesis is out of balance, meaning there is either too much or too little blood vessel growth, disease can emerge. Keeping angiogenesis in balance within the body is one of our key defenses against disease.
Educating patients, caregivers, clinicians and advocates
We believe better information leads to better health outcomes. Our global, patient-centered initiatives educate key stakeholders about the important role of angiogenesis in disease and health. Our key initiatives focus on preventing vision loss, defeating cancer and use diet and lifestyle to protect health. Many of our campaigns are also translated into Spanish, French, Italian, German, Japanese and Portuguese for increased reach.
Ang-2 plays an important role in retinal disorders, including AMD, DME, and RVO. Retinal vascular disease is about much more than VEGF, and targeting VEGF doesn’t cure these diseases. The interplay of the Ang-2/Tie2 signaling pathway with VEGF and other cellular components plays an important role in multiple retinal disorders. Ang-2 is the facilitator of multiple cellular activities which mediate vascular leakage, pericyte detachment, inflammation, and neovascularization.